Local cerebral blood flow in the conscious rat as measured with 14C-antipyrine, 14C-iodoantipyrine and 3H-nicotine.
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منابع مشابه
Measurement of local cerebral blood flow with iodo [14C] antipyrine.
The autoradiographic diffusible tracer technique for the measurement of local cerebral blood flow was originally designed for use with the radioactive, inert gas 131I-labeled trifluoroiodomethane and is applicable only with tracers that exhibit unrestricted diffusion through the blood-brain barrier. Because of the technical problems associated with the use of gaseous tracers, a suitable nonvola...
متن کاملRegional cerebral blood flow in conscious stroke-prone spontaneously hypertensive rats.
Regional cerebral blood flow (rCBF) was measured autoradiographically with [14C]iodoantipyrine as a diffusible tracer in two strains of conscious normotensive rats (Wistar Kyoto and local Wistar) and in two groups of spontaneously hypertensive stroke-prone rats (SHRSP) with a mean arterial pressure (MAP) below or above 200 mm Hg. In spite of the large differences in arterial pressure, rCBF did ...
متن کاملMeasurement of regional cerebral blood flow with antipyrine-14C in awake cats.
RmvIctx, MARTIN, JANE JEHLE, LOUIS SOKOLOFF, AND SEYMOUR s. KETY. Measurement of regional cerebral blood flow with antt$yrine-14C in awake cats. J. Appl. Physiol. 27(2): 296-300. 1969.-Antipyrine-14C was utilized for the quantitative measurement of regional cerebral blood flow in cats by means of an autoradiographic technique. The advantages of this technique over a previously described method ...
متن کاملLabeling of metabolic pools by [6-14C]glucose during K(+)-induced stimulation of glucose utilization in rat brain.
[6-14C]Glucose is the tracer sometimes recommended to assay cerebral glucose utilization (CMRglc) during transient or brief functional activations, but when used to study visual stimulation and seizures in other laboratories, it underestimated CMRglc. The metabolic fate of [6-14C]glucose during functional activation of cerebral metabolism is not known, and increased labeling of diffusible metab...
متن کاملEffects of immobilization stress on regional cerebral blood flow in the conscious rat.
Immobilization stress of conscious, normotensive, freely breathing 10-month-old Wistar-Kyoto rats produced an overall decline in regional cerebral blood flow (rCBF), as measured with [14C]iodoantipyrine, except at the frontal lobe. In 14 brain regions, rCBF fell by an average of 14.3% after 5 min of immobilization and by 11.9% after 15 min. Immobilization stress also stimulated hyperventilation...
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عنوان ژورنال:
- Stroke
دوره 10 1 شماره
صفحات -
تاریخ انتشار 1979